Study on quality control of Inula salsoloides from different producing areas in Xinjiang
- VernacularTitle:不同产地新疆沙旋覆花药材的质量控制研究
- Author:
Tingting ZHAO
1
;
Junting GUO
1
;
Xiaocui CAI
1
;
Talpbek YESEM
1
;
Guihua LIU
1
Author Information
1. Xinjiang Key Laboratory of Uyghur Medicine，Xinjiang Institute of Materia Medica，Urumqi 830011，China
- Publication Type:Journal Article
- Keywords:
Inula salsoloides from Xinjiang;
thin-layer chromatography identification;
microscopic identification;
content determination;
entropy weight-TOPSIS method
- From:
China Pharmacy
2026;37(12):1567-1572
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To control the quality of Inula salsoloides from different producing areas in Xinjiang. METHODS The macroscopic and microscopic identification of medicinal materials was performed using conventional morphological and microscopic observation methods. Thin-layer chromatography（TLC）was applied for the qualitative identification of chlorogenic acid in the medicinal materials. In ac cordance with the General Principles in Volume Ⅳ of the 2025 edition of the Chinese Pharmacopoeia ， the contents of water， total ash， acid-insoluble ash， and extractives of the samples were determined. High-performance liquid chromatography was used to measure the contents of chlorogenic acid， isoquercitrin， and quercetin. Taking water， total ash， acid-insoluble ash， extractives， and the contents of chlorogenic acid， isoquercitrin， and quercetin as evaluation indices， the entropy weight-TOPSIS method was adopted to comprehensively evaluate the quality of 18 batches of samples. RESULTS I. salsoloides from Xinjiang exhibited distinct macroscopic and microscopic characteristics， and the qualitative TLC identification results for chlorogenic acid were clear and reliable. The water content ranged from 6.20% to 7.23%， the total ash content from 12.27% to 15.80%， the acid-insoluble ash content from 1.89% to 2.57%， and the extractive contents from 21.24% to 28.09%. The contents of chlorogenic acid， isoquercitrin， and quercetin were 0.198 5 to 2.335 0 mg/g， 0.014 5 to 0.402 8 mg/g， and 0.016 5 to 0.578 7 mg/g， respectively. The comprehensive closeness degrees of 18 batches of samples were 0.106 to 0.673. CONCLUSIONS The established quality control method is stable and reliable， which can be applied to the quality control of I.salsoloides ， there are significant differences in the quality of medicinal materials from different producing areas.
