Timing of endoscopic treatment for acute esophagogastric variceal bleeding in liver cirrhosis： Controversies and challenges

Xinhui LI; Xingshun QI; Xiaofeng LIU; Daiming FAN; Jing WANG

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Timing of endoscopic treatment for acute esophagogastric variceal bleeding in liver cirrhosis： Controversies and challenges

VernacularTitle:肝硬化急性食管胃静脉曲张出血的内镜治疗时机：争议与挑战
Author: Xinhui LI ¹ ; Xingshun QI ² ; Xiaofeng LIU ³ ; Daiming FAN ⁴ ; Jing WANG ³
Author Information

1. Graduate School， Shandong First Medical University & Shandong Academy of Medical Sciences， Jinan 250117， China
2. Department of Gastroenterology， General Hospital of Northern Theater Command of PLA， Shenyang 110840， China
3. Department of Gastroenterology， The 960th Hospital of Joint Logistics Support Force of PLA， Jinan 250031， China
4. Department of Gastroenterology， Xijing Hospital， Air Force Medical University of PLA， Xi’an 710032， China
Publication Type:Review
Keywords: Liver Cirrhosis; Esophageal and Gastric Varices; Hemorrhage; Endoscopy， Gastrointestinal
From: Journal of Clinical Hepatology 2026;42(5):1178-1184
CountryChina
Language:Chinese
Abstract: Acute esophagogastric variceal bleeding （AEGVB） is one of the life-threatening complications of decompensated cirrhosis. Endoscopy is the main method for the diagnosis and treatment of AEGVB， and endoscopic treatment can effectively control acute bleeding and alleviate or eliminate varices. However， there is still a lack of consistent recommendations for the timing of endoscopic examination and intervention for AEGVB in related guidelines in China and globally. Existing studies in China and globally have low quality of evidence， with significant variations in the definition of “early endoscopy” and inconsistent conclusions. This article reviews the research advances in the timing of endoscopic treatment for AEGVB in liver cirrhosis， points out the controversies over the optimal timing of treatment， and discusses future research directions in this field.