Inhibitory effect and mechanism of traditional Chinese medicine on liver fibrosis and hepatic sinusoidal capillarization

VernacularTitle:中药对肝纤维化肝窦毛细血管化的抑制作用及其机制
Author: Long WANG ¹ ; Li MA ¹ ; Andong SONG ¹ ; Guohua LI ¹ ; Tingting JIA ²
Author Information

1. School of Traditional Chinese Medicine， Ningxia Medical University， Yinchuan 750004， China
2. Ningxia Hui Autonomous Region Hospital of Traditional Chinese Medicine and Chinese Medicine Research Institute， Yinchuan 750021， China
Publication Type:Review
Keywords: Hepatic Fibrosis; Hepatic Sinusoidal Capillary Metaplasia; Drugs， Chinese Herbal; Therapeutics
From: Journal of Clinical Hepatology 2026;42(5):1166-1171
CountryChina
Language:Chinese
Abstract: Hepatic sinusoidal capillarization is the first event in the process of fibrogenesis， and inhibiting hepatic sinusoidal capillarization can effectively improve the pathological process of liver fibrosis. Various studies have shown that traditional Chinese medicine can significantly inhibit hepatic sinusoidal capillarization. This article systematically reviews the effective constituents， monomers， and compound prescriptions of traditional Chinese medicine， summarizes their mechanism of action in inhibiting hepatic sinusoidal capillarization， and analyzes the theoretical core of traditional Chinese medicine in inhibiting hepatic sinusoidal capillarization from the perspective of traditional Chinese medicine， in order to provide ideas and literature support for the treatment of liver fibrosis.