Ideal Candidates for Mitral Transcatheter Edge-to-Edge Repair:Anatomic and Clinical Indications
- Author:
Jong-Il PARK
1
;
Ung KIM
Author Information
- Publication Type:Review Article
- From: Journal of Cardiovascular Intervention 2026;5(1):23-37
- CountryRepublic of Korea
- Language:English
- Abstract: Mitral regurgitation (MR) is a common valvular heart disease that is associated with increased morbidity and mortality, especially in patients of advanced age or with multiple comorbidities.Transcatheter edge-to-edge repair (TEER) has emerged as a minimally invasive alternative to surgery for appropriately selected patients with primary or secondary MR. Although TEER is now established for patients who meet strict anatomical and clinical criteria, recent evidence from randomized trials and registries has broadened its application to include patients with atrial functional MR, severe ventricular dysfunction, acute MR, complex mitral anatomy, and failed prior surgery. Advancements in device technology, such as the introduction of multiple clip sizes and independent leaflet grasping, as well as improvements in imaging techniques, have further enhanced procedural safety and efficacy. This review summarizes the anatomical and clinical considerations for TEER, evaluates both trial-based and real-world data on emerging indications, and discusses technical factors and patient subsets in which TEER may provide benefits beyond current guideline-directed recommendations.
