Review on relationship between migraine and stroke
- VernacularTitle:Мигрень, тархины харвалт хоорондын хамаарал: Системт тойм судалгаа
- Author:
Delgermaa Ts
1
;
Burmaajav B
2
;
Tsagaankhuu G
1
Author Information
1. MNUMS, Shool of Medicine, Department of Neurology
2. Ach Medical University
- Publication Type:Review
- Keywords:
Migraine;
Stroke;
Vascular risk factors
- From:Mongolian Medical Sciences
2026;215(1):140-158
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Recent meta-analyses have consistently demonstrated a relationship between migraine and
stroke, which is well-defined for ischemic stroke and migraine with aura, is even stronger
in females on oral contraceptives or smokers. However, there seems to be no clear-cut
association between stroke in migraineurs and the common vascular risk factors, at least
in the young adult population. Migraineurs also run an increased risk of hemorrhagic stroke,
while the association between migraine and cardiovascular disease remain poorly defined.
Objective:The aim was to conduct a systematic review of published sources on the relationships
between migraine and stroke in young people.
Methods:The research sources were searched using keywords such as “Migraine”, “Headache”,
“Migraine-infarct”, “Vascular risk factors”, “Silent stroke”, “Leukoaraiosis”, “Patent foramen
ovale”, “Dissection”, “hereditary vascular disease” from the works published in international
platforms such as Cochrane Library, Datebase, Medline, PubMed, Google Scholar, and Web
of Science, and relevant information and data were selected from the collected sources and
a review article was developed.
Results:It has been demonstrated that there is an increased frequency of ischemic lesions in the
white matter of migraineurs, especially silent infarcts in the anterior and posterior circulation
territories in patients with at least 10 attacks per month. Although there is a higher prevalence
of patent foramen ovale (PFO) in migraineurs, the relationship between migraine and PFO
remains controversial and PFO closure is not a recommended procedure to prevent migraine.
As an increased frequency of cervical artery dissections has been observed in migrainous
patients, it has been hypothesized that migraine may represent a predisposing factor for
cervical artery dissection.
Conclusion:Based on the research evidence, there is a clear relationship between
symptomatic migraine (with aura) and silent brain infarction, so early detection and treatment
of vascular risk factors are necessary in migraine patients.
- Full text:2026070409175406445MAUS-2026-215(1)-140-158.pdf
