Clinical Outcome Prediction by High-Resolution Computed Tomography and Echocardiography Assessment of Pulmonary Hypertension in Patients with Bronchiectasis
- Author:
Inhan LEE
1
;
Joon-Sung JOH
;
Ji Yeon LEE
;
Joohae KIM
;
Sooim SIN
;
Hyeon-Kyoung KOO
;
Ina JEONG
Author Information
- Publication Type:Original Article
- From:Tuberculosis and Respiratory Diseases 2026;89(2):297-305
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:To evaluate the association between pulmonary hypertension and hospital admission rates in patients with bronchiectasis.
Methods:We retrospectively analyzed data from 130 bronchiectasis patients at the National Medical Center, Korea (November 2012 to October 2022). Pulmonary hypertension was evaluated using high-resolution computed tomography (CT) and echocardiography. Patients were categorized into two groups based on the diameter of the main pulmonary artery (mPA). Logistic regression analysis was performed to identify risk factors associated with hospitalization.
Results:Forty patients had suspected pulmonary hypertension on echocardiography. A higher percentage of patients with mPA diameter >29 mm (n=61) had a history of previous exacerbations, elevated echocardiographic parameters related to pulmonary hypertension, and reduced lung function, compared to those with mPA diameter ≤29 mm (n=69). In univariate analysis, the hospitalization group showed increased mPA diameter; pulmonary artery to aorta ratio; involvement of lung lobes, cavities, and nodules; and increased systolic pulmonary artery pressure and peak tricuspid regurgitation velocity. In multivariate analysis, mPA diameter >29 mm (adjusted odds ratio [OR], 2.47; 95% confidence interval [CI], 1.14 to 5.32) and the involvement of more than two lobes (adjusted OR, 2.57; 95% CI, 1.14 to 5.77) were significant risk factors for hospitalization.
Conclusion:The CT parameters demonstrated comparable accuracy to models that incorporated echocardiographic data to predict hospitalization in bronchiectasis patients.
