Burkitt Lymphoma with Hepatic Involvement Diagnosed by Contrast-Enhanced Ultrasonography and Liver Biopsy: A Case Report
10.18525/cu.2025.10.2.129
- Author:
So Hyun JEON
1
;
Young Hyeon AHN
;
Jeong-Ju YOO
;
Sae Hwan LEE
;
Soung Won JEONG
;
Jae-Young JANG
;
Susie CHIN
;
Young Seok KIM
;
Sang Gyune KIM
Author Information
1. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea
- Publication Type:Case Report
- From:
Clinical Ultrasound
2025;10(2):129-134
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 68-year-old man with no significant medical history was referred for evaluation of incidentally detected hepatic and splenic lesions found during imaging for rib fractures. Cross-sectional imaging with computed tomography, magnetic resonance imaging, and fluorodeoxyglucose F18 positron-emitting tomography revealed multiple variable-sized masses in the liver and spleen. Contrast-enhanced ultrasound (CEUS) using Sonazoid showed mild arterial enhancement, early washout, and a corresponding perfusion defect in the delayed (Kupffer) phase. Ultrasound- guided liver biopsy confirmed Burkitt lymphoma. The patient received systemic chemotherapy, resulting in marked regression of hepatic and splenic lesions on follow-up imaging. This case highlights the diagnostic value of CEUS in characterizing atypical hepatic lesions and its potential to raise early suspicion for lymphoma, facilitating timely biopsy and management.
