Pediatric Idiopathic Cutaneous Pseudolymphoma of the Lower Eyelid:A Case Report
- Author:
Yejin KANG
1
;
Jaehoon SHIN
;
Hoon KANG
;
Jung Eun KIM
Author Information
1. Departments of Dermatology, Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
- Publication Type:Case Report
- From:Korean Journal of Dermatology
2025;63(6):178-182
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cutaneous pseudolymphoma refers to a group of benign lymphoid proliferations that mimic cutaneous lymphomas clinically and histologically. Here, we describe a case involving a 13-year-old boy who presented with an asymptomatic, solitary, dome-shaped, skin-colored nodule on the left lower eyelid, initially suspected to be a soft fibroma or neurofibroma. Histopathological examination with immunohistochemical analysis showed a dense dermal lymphoid infiltrate predominantly composed of CD3＋, CD5＋ T cells, interspersed with CD20＋ B cells and CD38＋ plasma cells, without evidence of light chain restriction on kappa/lambda in situ hybridization. We diagnosed the lesion as cutaneous pseudolymphoma. Given the benign nature and previous unsuccessful topical treatments, we began treatment with intralesional corticosteroid therapy (triamcinolone acetonide, 5 mg/mL), resulting in significant clinical improvement within 1 month. This case underscores the importance of comprehensive histologic and immunophenotypic assessments to differentiate pseudolymphoma from early-stage cutaneous lymphomas, particularly in pediatric patients.
