Leukocyte Reduction Filter Occlusion Caused by a Large Clot in a Red Blood Cell Unit
10.17945/kjbt.2026.37.1.3 2
- Author:
Jongbin WEE
1
;
Aeheon JEONG
;
Sooin CHOI
Author Information
1. Department of Laboratory Medicine and Genetics, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea
- Publication Type:Illustrated
- From:Korean Journal of Blood Transfusion
2026;37(1):32-33
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 91-year-old male patient with chronic obstructive pulmonary disease in the intensive care unit was issued a red blood cell unit. Shortly after issuance, the transfusion failed because of an occlusion in the bedside leukocyte reduction filter. A small clot was observed at the spike portion of the returned filter, but the transfusion failure persisted despite replacement of the filter. On the bedside inspection, a large, irregularly shaped dark clot, approximately 2×2.5 cm in size, was observed within the blood bag, obstructing the filter spike and preventing blood flow. The unit was retrieved and classified as unsuitable for transfusion, and the supplying blood center was notified. A replacement red blood cell unit was then issued. This case highlights the importance of careful visual inspections and prompt management of abnormal blood components to ensure transfusion safety.
