Diagnostic Imaging Features of Cranial Mediastinal Osteosarcoma in a Dog
10.17555/jvc.2025.42.4.225
- Author:
Jihui BAE
1
;
Hojung CHOI
;
Youngwon LEE
Author Information
1. College of Veterinary Medicine, Chungnam National University, Daejeon 34134, South Korea
- Publication Type:Case Report
- From:
Journal of Veterinary Clinics
2025;42(4):225-230
- CountryRepublic of Korea
- Language:English
-
Abstract:
Metastasis to the mediastinum from axial skeletal osteosarcoma (OSA) is rare in dogs, and extraskeletal osteosarcoma originating from the mediastinum is an extremely rare malignant tumor in the veterinary literature. A 12-year-old Maltese dog was presented with intrathoracic masses on thoracic radiographs. Computed tomography revealed two distinct osteoblastic cranial mediastinal masses and a bone lesion involving the second thoracic vertebra. A biopsy was performed on one of the mediastinal masses. A histopathological examination confirmed the presence of an osteoid matrix with atypical mesenchymal proliferation, consistent with OSA. Accordingly, two potential origins for the mediastinal OSA were considered: vertebral OSA with mediastinal metastasis or primary mediastinal extraskeletal OSA with vertebral metastasis. This case represents a rare occurrence of primary or metastatic OSA in an unusual anatomical location. Radiography and computed tomography examinations are useful for diagnosing tumors with mineralized opacities.
