Atypical Fibroma and Fibrosarcoma Derived from Cutaneous Ganglion Cell-Like Cells in Ten Djungarian Hamsters (Phodopus sungorus)
10.17555/jvc.2024.41.1.65
- Author:
Ji-Youl JUNG
1
;
Han-Na KIM
;
Da-Ye NAM
;
So-Jeong YIM
;
Jae-Hoon KIM
Author Information
1. College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 63243, Korea
- Publication Type:Case Report
- From:
Journal of Veterinary Clinics
2024;41(1):65-70
- CountryRepublic of Korea
- Language:English
-
Abstract:
Ten cutaneous masses from Djungarina hamsters (Phodopus sungorus) were diagnosed as nine atypical fibromas and one fibrosarcoma derived from cutaneous ganglion cell-like cells. Among these patients, nine were male and one was female. Histologically, these abnormal masses were composed of spindle-shaped or polygonal neoplastic ‘ganglion cell-like’ cells with abundant amphophilic vacuolated cytoplasm. Immunohistochemically, these neoplastic cells were stained for vimentin, S100, and neuron-specific enolase. Out of 9 males, 3 showed positive reactions to the androgen receptor. This report provides a detailed histologic and immunohistochemical characterization of atypical fibroma, fibrosarcoma, and the tumorigenesis of ganglion cell-like cells in Djungarian hamsters.
