Identifying early risk factors for chronic pain development following vertebral fractures: a single-center prospective cohort study
- Author:
Yutaro KONDO
1
;
Hideki KATAOKA
;
Kyo GOTO
;
Koichi NAKAGAWA
;
Yutaro NOMOTO
;
Junichiro YAMASHITA
;
Kaoru MORITA
;
Nobuya ASO
;
Yuki NSHI
;
Junya SAKAMOTO
;
Minoru OKITA
Author Information
- Publication Type:Clinical Study
- From:Asian Spine Journal 2025;19(6):928-938
- CountryRepublic of Korea
- Language:English
-
Abstract:
Methods:Hospitalized patients with acute VFs underwent assessment of vertebral morphology and paraspinal muscles. Two weeks post-admission, patients were evaluated for pain intensity (using the Verbal Rating Scale [VRS]), pain sensitivity (Pressure Pain Threshold [PPT] and Conditioned Pain Modulation), psychological factors, physical function, and activity levels. At 12 weeks, patients were categorized into CP and non-CP (NCP) groups based on VRS scores. Between-group comparisons and logistic regression analysis were performed to identify predictors of CP development.
Results:The CP group exhibited significantly lower remote PPT and reduced low-intensity physical activity time, but higher Pain Catastrophizing Scale rumination scores and prolonged 5-Times Sit-to-Stand Test (5SST) compared to the NCP group. Logistic regression identified prolonged 5SST and reduced low-intensity physical activity as independent predictors of CP development.
Conclusions:Prolonged 5SST and reduced low-intensity physical activity may predict CP development after VFs. Early assessment of these factors may facilitate CP risk screening in hospitalized patients with VFs.
