Single-center experience with pediatric short bowel syndrome: clinical outcomes based on etiology and anatomical type in a retrospective cohort study
10.4174/astr.2026.110.3.194
- Author:
Honam HWANG
1
;
Dayoung KO
;
Joong Kee YOUN
;
Hee-Beom YANG
;
Hyun-Young KIM
Author Information
1. Department of Pediatric Surgery, Seoul National University Children’s Hospital, Seoul, Korea
- Publication Type:ORIGINAL ARTICLE
- From:Annals of Surgical Treatment and Research
2026;110(3):194-201
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:Short bowel syndrome (SBS) is a critical condition in pediatric patients. It often results in dependence on parenteral nutrition (PN) and significant morbidity. This study aimed to review pediatric SBS patients from a single center and analyze clinical outcomes based on etiology and anatomical type.
Methods:A total of 55 patients diagnosed with SBS at our institution from January 2004 to December 2018 were retrospectively analyzed. Clinical demographics and outcomes including growth and PN dependence were evaluated according to etiology and anatomical type.
Results:The predominant cause of SBS was necrotizing enterocolitis (NEC). At the last follow-up, the mean weight-forage (z-score) was –2.00 ± 2.07 and 52.7% of patients were weaned off PN. Catheter-related bloodstream infection and PN-associated liver disease occurred in 36.4% and 20.0% of cases, respectively. Patients with motility disorders exhibited lower weight-for-age and longer durations of PN than those with NEC or intestinal atresia. Additionally, outcomes varied significantly by anatomical type, with type I patients showing higher PN dependence and lower rates of successful weaning off PN than type III patients.
Conclusion:The study suggests that clinical outcomes in pediatric SBS patients can vary depending on underlying etiology and anatomical type, indicating that tailored interventions might enhance patient outcomes. Further research is needed to identify independent prognostic factors for SBS and improve the quality of life of SBS children.
