Multiple autoimmune syndrome in a dog presented with hematologic disease: a rare case report
- Author:
Jinyoung PARK
1
;
Chaewon SHIN
;
Minjeong KANG
;
Sumin CHA
;
Sung-Lim LEE
;
Dong-In JUNG
;
DoHyeon YU
;
Hyeona BAE
Author Information
- Publication Type:Case Report
- From:Korean Journal of Veterinary Research 2025;65(2):e11-
- CountryRepublic of Korea
- Language:English
- Abstract: Multiple autoimmune syndrome (MAS) refers to the occurrence of three or more autoimmune diseases in a patient. This case describes a 12-year-old neutered male Shih Tzu with fever and neutropenia, previously diagnosed with immune-mediated thrombocytopenia, immune-mediated hemolytic anemia, and inflammatory bowel disease. Blood tests revealed leukopenia and neutropenia, and immune-mediated neutropenia was suspected after ruling out other causes of neutropenia. The dog showed no response to antibiotics, but treatment with prednisolone (2 mg/kg q24h) led to improvement. This case highlights the potential for MASs to occur in dogs and underscores the importance of their recognition in the diagnosis and management of immune-mediated diseases.
