Kyrieleis Plaques Associated with Ocular Toxoplasmosis: Case Report
10.21561/jor.2026.11.1.60
- Author:
Moon Young CHOI
1
;
Jae Pil SHIN
Author Information
1. Department of Ophthalmology, Namyangju Nune Eye Hospital, Namyangju, Korea
- Publication Type:CASE REPORT
- From:
Journal of Retina
2026;11(1):60-63
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:We report two cases of Kyrieleis plaques associated with ocular toxoplasmosis.Case summary: A 65-year-old man presented with decreased vision in the right eye. Fundus examination showed vitreous inflammation and small peripheral retinochoroiditis. Serologic testing revealed elevated Toxoplasma gondii immunoglobulin G (IgG) titers. Other infectious or autoimmune causes were excluded. The patient was treated with oral sulfamethoxazole/trimethoprim. During work-up, multiple segmental whitish opacities developed along retinal arteries, consistent with Kyrieleis plaques. These gradually regressed as inflammation subsided. A 66-year-old man presented with unilateral vitritis and peripheral chorioretinal atrophic lesion. Laboratory tests were positive for T. gondii IgG and negative for other infectious or inflammatory markers. The patient received oral sulfamethoxazole/trimethoprim and showed gradual improvement. Segmental periarterial opacifications appeared during recovery but resolved completely with inflammation control.
Conclusions:Recognition of this distinctive but benign finding is essential to distinguishing it from retinal artery emboli or occlusion, preventing unnecessary systemic work-up, and supporting the appropriate management of inflammatory ocular diseases.
