Anti–N-Methyl-D-Aspartate receptor encephalitis: Seizures and psychosis – A case report
- Author:
Ma. Cassandra C. Alfonso
1
;
Ken Manongas
1
;
Criselda Tagayuna
Author Information
- Publication Type:Case Reports
- MeSH: Anti-N-Methyl-D-Aspartate Receptor Encephalitis; N-Methylaspartate; D-Aspartic Acid; Receptors, N-Methyl-D-Aspartate
- From: Philippine Journal of Internal Medicine 2025;63(4):1-4
- CountryPhilippines
- Language:English
- Abstract: Anti–N-methyl-D-aspartate (NMDA) receptor encephalitis is a neurologic disease first identified by Dr Josep Dalmau and colleagues at the University of Pennsylvania in 2007. The first confirmed case of anti-NMDA receptor encephalitis reported in the Philippines was published in the Philippine Journal of Neurology last August 2012; it was entitled “A rare disease with a unique feature: Anti-NMDA receptor encephalitis and mesenteric teratoma”. Anti-NMDA receptor encephalitis is an autoimmune disease where the body creates antibodies against the NMDA receptors in the brain, in which antibodies disrupt normal brain signaling, causing brain swelling, or encephalitis; many reports claim that it is often misdiagnosed due to atypical presentation that overlaps neurologic and psychiatric symptoms, in which it is difficult to recognize, and that may delay management.
- Full text:20260630142432755651-2023-273.pdf
