Comparison of Longer and Shorter Hemodialysis Duration on Nutritional Status and Quality of Life of Hemodialysis Patients

Nur Samsu; Devi Santi Fatmawati; Farida Wibisono; Kartin Kartin; Wahyu Wulandari; Ayu Radyan Sephani; Renny Tandya; Angelina Gemilang Kartikasari Kosasih

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Comparison of Longer and Shorter Hemodialysis Duration on Nutritional Status and Quality of Life of Hemodialysis Patients

Author: Nur Samsu ¹ ; Devi Santi Fatmawati ² ; Farida Wibisono ² ; Kartin Kartin ³ ; Wahyu Wulandari ⁴ ; Ayu Radyan Sephani ⁵ ; Renny Tandya ⁵ ; Angelina Gemilang Kartikasari Kosasih ⁵
Author Information

1. Department of Internal Medicine, Division of Nephrology and Hypertension, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia http://orcid.org/0000-0003-4610-3796
2. Dialysis unit of Wava Husada Hospital, Malang, Indonesia
3. Dialysis unit of Panti Nirmala Hospital, Malang, Indonesia
4. Dialysis Unit of Saiful Anwar General Hospital, Malang, Indonesia
5. Resident of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia
Publication Type:Observational Study
Keywords: subjective global assessment; SF-36 questionnaire; blood flow rate; dialysis time
MeSH: subjective global assessment; SF-36 questionnaire; blood flow rate; dialysis time
From: Acta Medica Indonesiana 2026;58(1):15-25
CountryIndonesia
Language:English
Abstract: Abstract:Background: Important determinants of dialysis adequacy are blood flow rate (BFR) and dialysis time. This study aimed to evaluate the impact of BFR and duration of dialysis session on nutritional status and quality of life (QoL) in hemodialysis (HD) patients. Methods: Real-world evidence studies (RWE) of 3 HD units that differ in BFR and/or dialysis time. Group I, HD 5 hours and BFR 200-250 mL/minute; group II, HD 4 hours and BFR 270-320 mL/minute, and group III, HD 4 hours and BFR 200-250 mL/minute. All HD units use the same dialysate flow and dialysis frequency. The 3-point Subjective Global Assessment (SGA) scale is used to assess nutritional status, while QOL is assessed using the SF-36. Results: There were 291 chronic HD patients with an average age of 51 (12.3) years, 50.5% were male. The proportion of SGA classes between groups did not differ significantly. Group I was associated with significantly higher PF and RP domain scores of PC and VT domain scores of MC compared to Group III. On the other hand, Group II was associated with significantly lower VT and MH domain scores of MC compared to Group I, while the other domains were not significantly different. In general, Group III had the lowest SF-36 scores compared to the other 2 groups. Conclusion: Duration of HD was not associated with nutritional status. Compared with 4-hour HD but with a faster BFR, 5-hour HD was associated with higher Mental Component QOL scores, but not Physical Component scores.
Full text:2026062915225627121oa2-Nur Samsu.pdf