Exploration of Determinants of Adherence to Antihypertensive Medication: A Multilevel Analysis of the Fifth Wave of the Indonesia Family Life Survey
10.47836/mjmhs.v22i1.1432
- Author:
Mustara
1
;
Hartono2
2
;
Eti Poncorini PamungkasarI
2
;
Nur Hafidha Hikmayani
2
Author Information
1. Doctoral Program of Public Health, Faculty of Medicine, Universitas Sebelas Maret, 57126 Surakarta, Central Java, Indonesia
2. Department of Public Health, Faculty of Medicine, Universitas Sebelas Maret, 57126 Surakarta, Central Java, Indonesia
- Publication Type:Journal Article
- Keywords:
Hypertension;
Antihypertensive drug;
Medication adherence;
Multilevel analysis;
Indonesia
- From:
Malaysian Journal of Medicine and Health Sciences
2026;22(No. 1):1-10
- CountryMalaysia
- Language:English
-
Abstract:
Introduction: The prevalence of hypertension in Indonesia is increasing, but adherence to antihypertensive medication remains low. Previous studies have mostly examined medication adherence determinants separately at individual and environmental levels, with limited research integrating these factors comprehensively. This study investigates
the factors influencing adherence to antihypertensive medication in Indonesia. Materials and methods: The study
utilised data from the IFLS-5, involving 2,334 respondents aged ≥ 15 years diagnosed with hypertension. Multilevel
logistic regression is used to identify predictor variables for medication adherence. The effect size is determined by
odds ratio (OR) and significance at p-value < 0.05. Result: Contextual household factors influence up to 22.45%
of the variation in adherence to antihypertensive medication. Variables that influence medication adherence are
comorbid diabetes (OR = 1.53, 95% CI: 1.04 – 2.23, p=0.029), had a heart attack (OR = 2.84, 95% CI: 1.79-4.52,
p<0.0001), comorbid stroke (OR = 2.79, 95% CI: 1.59 – 4.90, p<0.0001), routine medical check-up (OR = 1.70,
95% CI: 1.23-2.36, p=0.001), feel healthy (OR = 0.59, 95% CI: 0.43-0.72, p<0.0001), aged ≥ 47 years (OR =
2.84, 95% CI: 2.10-3.84, p<0.0001), and households with social protection cards (OR = 0.61, 95% CI: 0.40-0.93,
p=0.022). Conclusion: Higher adherence occurs in hypertensive patients with diabetes, stroke, heart attack, routine
check-ups, and aged ≥ 47 years. However, lower in feeling healthy and households with social protection cards.
Programs to improve medication adherence should focus on hypertension without comorbidities, aged <47 years,
feeling healthy, and low-income families.
- Full text:2026062611015199565+1780+JAN+C.pdf
