Neuroimmune mechanisms and perioperative management strategies for post-cataract surgery dry eye
10.3980/j.issn.1672-5123.2026.7.13
- VernacularTitle:白内障术后干眼的神经免疫机制及围手术期防治策略
- Author:
Xuejiao WANG
1
;
Fangliang YU
1
Author Information
1. Affiliated Eye Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China; Nanchang University, Nanchang 330006, Jiangxi Province, China
- Publication Type:Journal Article
- Keywords:
post-cataract surgery dry eye;
surgery-induced dry eye;
neuroimmune modulation;
psychological factors;
meibomian gland dysfunction;
perioperative management
- From:
International Eye Science
2026;26(7):1185-1191
- CountryChina
- Language:Chinese
-
Abstract:
Post-cataract surgery dry eye(PCSDE)is a common complication, with an incidence of 9.2%-72.6%, and approximately 20% of patients experience persistent long-term symptoms. In the era of refractive cataract surgery, dry eye has become a critical factor affecting surgical satisfaction due to rising patient expectations for visual quality. Emerging evidence highlights that the interplay between neurosensory abnormalities and immune-inflammatory responses drives PCSDE chronicity, with psychoneurological factors gaining increasing attention. This review systematically examines PCSDE pathogenesis and contributing factors from this novel perspective, including surgical variables(incision design, operative duration, techniques), patient-related factors(age, meibomian gland function, systemic diseases, psychological status), and perioperative management(drug toxicity, disinfectant use). Additionally, based on the latest clinical evidence, comprehensive prevention and treatment strategies including preoperative optimization of ocular surface conditions, intraoperative ocular surface protection techniques, and personalized postoperative regimens are summarized. A deeper understanding of the multifactorial mechanisms of PCSDE is crucial for enhancing the quality of cataract surgery and improving patient outcomes. This review establishes a novel framework for PCSDE management based on neuro-immune-psychological interactions, offering crucial theoretical updates and practical guidance to enhance visual quality and patient satisfaction in refractive cataract surgery.
