Structural characteristics of lamina cribrosa and research progress in high myopia with primary open angle glaucoma
10.3980/j.issn.1672-5123.2026.7.09
- VernacularTitle:高度近视合并原发性开角型青光眼的筛板结构特征与研究进展
- Author:
Ying LI
1
;
Kunliang QIU
1
Author Information
1. Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong;Fifth Clinical Institute of Shantou University Medical College;Guangdong Engineering Technology Research Center of Precision Treatment for Ocular Diseases;Guangdong Engineering Research Center of Intelligent Diagnosis and Treatment for Ocular Diseases;Shantou Key Laboratory of Ocular Disease Prevention, Treatment and Research, Shantou 515000, Guangdong Province, China; Shantou University Medical College, Shantou 515000, Guangdong Province, China
- Publication Type:Journal Article
- Keywords:
high myopia;
primary open angle glaucoma;
lamina cribrosa;
optical coherence tomography
- From:
International Eye Science
2026;26(7):1163-1167
- CountryChina
- Language:Chinese
-
Abstract:
High myopia combined with primary open angle glaucoma is an increasingly concerned and complex disease in ophthalmology, and its pathogenesis is closely associated with multiple alterations in structural parameters of the lamina cribrosa. As the main supportive structure of the optic nerve, the lamina cribrosa plays an important role in pathophysiology of glaucoma through parameters including curvature, depth, defects, and thickness. Meanwhile, fundus alterations induced by high myopia may obscure typical glaucomatous features. Current research on the relationship between lamina cribrosa parameters and high myopia combined with primary open angle glaucoma still have certain limitations, particularly in terms of mechanism exploration and clinical application. Through systematically reviewing the relevant literature, this article aims to summarize the latest research advances on lamina cribrosa parameters in high myopia combined with primary open angle glaucoma, with a focus on discussing the potential and current limitations of these parameters as biomarkers for early diagnosis and prognosis assessment.
