Changes of optic nerve head morphology in high myopia
10.3980/j.issn.1672-5123.2026.7.02
- VernacularTitle:高度近视的视盘形态学改变
- Author:
Wenquan TANG
1
;
Fen NIE
1
;
Yulin LUO
1
Author Information
1. Department of Ophthalmology, the Affiliated Children's Hospital of Xiangya School of Medicine, Central South University;Hunan Children's Hospital, Changsha 410007, Hunan Province, China
- Publication Type:Journal Article
- Keywords:
high myopia;
optic nerve head;
morphology;
axial length
- From:
International Eye Science
2026;26(7):1110-1115
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To analyze the correlation of age, axial length(AL)and spherical equivalent(SE)with the morphology of optic nerve head(ONH)in high myopia(HM)patients.METHODS:In this retrospective study, the medical records of HM patients were reviewed, and were classified based on age, AL, and SE. Participants were stratified into three age subgroups: Age1(<20 y), Age2(20-29 y), and Age3(≥30 y). For SE, participants were classified into three subgroups: SE1(-9 D≤SE<-6 D), SE2(-12 D≤SE<-9 D), and SE3(SE<-12 D). AL was further divided into four groups: AL1(<26 mm), AL2(26≤AL<27 mm), AL3(27≤AL<28 mm), and AL4(AL≥28 mm). The effects of different ages, AL, and SE on optic disc morphological parameters and their correlations were investigated.RESULTS:Totally 188 right eyes from 188 HM patients(65 males and 123 females)with mean age of 25.00±6.44 y were analyzed. No significant difference was observed in morphological data of ONH among the age groups(all P>0.05). The ONH tilt index and ONH rotation angle had no correlation with the age, AL, and SE. However, the optic disc-fovea distance(DFD), angle α, largest diameter(LD), short diameter(SD), and ONH area were significantly correlated with AL and SE(DFD: r=0.195, 0.221; angle α: r=-0.242, -0.266; LD: r=0.319, 0.295; SD: r=0.274, 0.225; ONH area: 0.310, 0.265; all P<0.01)but not with age(P>0.05). In HM, as the AL grew larger than 28 mm, the angle α was smaller and the DFD was larger significantly. CONCLUSION:The DFD and angle α can be used as evaluation indicators for the changes of ONH morphology in HM patients. The main cause of morphology change may be related to AL and SE increase rather than age.
