Disease-syndrome Combination Animal Models in Andrology of Traditional Chinese Medicine： A Review and Prospects
10.13422/j.cnki.syfjx.20260244
- VernacularTitle:中医男科病证结合动物模型研究进展与展望
- Author:
Jigang CAO
1
;
Jianxiong LIU
2
;
Min XIAO
3
;
Xiaocui JIANG
3
;
Aidi LIANG
1
;
Xingyu JIANG
1
;
Yanyan ZHOU
4
;
Xiaoming YU
3
Author Information
1. School of Basic Medical Sciences， Hubei University of Chinese Medicine， Wuhan 430065， China
2. School of Chinese Medicine， Hubei University of Chinese Medicine， Wuhan 430065， China
3. Hubei Shizhen Laboratory， Wuhan 430065， China
4. Hubei Provincial Hospital of Traditional Chinese Medicine， Wuhan 430061， China
- Publication Type:Journal Article
- Keywords:
andrology of traditional Chinese medicine;
disease-syndrome combination;
animal model;
evaluation system
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(13):303-314
- CountryChina
- Language:Chinese
-
Abstract:
The disease-syndrome combination animal model in traditional Chinese medicine （TCM） andrology serves as an important bridge linking TCM theory with modern medical research， providing a key experimental platform for elucidating the 'syndrome-disease' correlation mechanism in male-specific diseases and for screening effective prescriptions. This article reviews recent progress in animal model research on common TCM andrological diseases， including prostatic diseases， sexual dysfunction， and male infertility， with a focus on analyzing the application， advantages， and disadvantages of various modeling strategies， such as immune induction， hormonal intervention， and multi-factor combination across different syndrome types. However， despite breakthroughs in model construction techniques， current research still faces several challenges， including insufficient standardization of syndrome differentiation and difficulties in quantifying TCM-specific indicators. Future studies need to optimize model evaluation systems by integrating modern technologies， in order to promote the standardization and internationalization of TCM andrology research.
