Research progress on the role of macrophages in atherosclerosis
10.19405/j.cnki.issn1000–1492.2026.04.024
- VernacularTitle:巨噬细胞在动脉粥样硬化中的作用研究进展
- Author:
Wenxiu MA
1
;
Li BAI
2
;
Wen MA
1
;
Tingting QI
1
;
Haonan ZHANG
3
;
Xuan WANG
4
;
Xin ZHANG
4
Author Information
1. Graduate School of Baotou Medical College， Inner Mongolia University of Science and Technology， Baotou 014010
2. Central Laboratory， First Affiliated Hospital of Baotou Medical College， Inner Mongolia University of Science and Technology， Baotou 014010
3. Dept of Research， First Affiliated Hospital of Baotou Medical College， Inner Mongolia University of Science and Technology， Baotou 014010
4. Dept of Cardiology， First Affiliated Hospital of Baotou Medical College， Inner Mongolia University of Science and Technology， Baotou 014010
- Publication Type:Review
- Keywords:
macrophages;
atherosclerosis;
lipid;
inflammation;
polarization;
treatment
- From:
Acta Universitatis Medicinalis Anhui
2026;61(4):770-775
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis （AS） is a chronic and inflammatory vascular disease. Macrophages are common immune cells and play an important role in the development of AS. In recent years， research has found that the formation of AS plaques is closely related to pathological and physiological processes such as macrophage polarization， energy metabolism， and lipid phagocytosis. This review aims to summarize the mechanism of macrophages in the development of AS， and to explore potential therapeutic methods for delaying AS by regulating macrophages， providing new ideas for the treatment and research of AS.
