Analyses of the epidemiological and clinical characteristics of 21 confirmed monkeypox cases in a district of Chengdu City
10.19428/j.cnki.sjpm.2026.250302
- VernacularTitle:成都市某区21例猴痘确诊病例临床及流行病学特征分析
- Author:
Kejun LIAO
1
;
Yawen TIAN
2
;
Shuhua REN
2
;
Yong YUE
2
;
Yunfeng HE
2
;
Caibin YANG
2
;
Xuanji CHEN
2
;
Jiangchao LI
2
;
Wan YANG
2
;
Jie LI
1
Author Information
1. Meishan City Center for Disease Control and Prevention, Meishan, Sichuan 620000, China
2. Chengdu Hi-tech Zone Center for Disease Control and Prevention, Chengdu, Sichuan 610041, China
- Publication Type:Journal Article
- Keywords:
monkeypox;
men who have sex with men;
individual infected with human immunodeficiency virus;
clinical characteristic;
epidemiological characteristic;
epidemic prevention and control
- From:
Shanghai Journal of Preventive Medicine
2026;38(3):231-234
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo analyze the epidemiological and clinical characteristics of the 21 confirmed monkeypox cases in a district of Chengdu City, and to provide scientific guidance for the prevention and control of subsequent monkeypox epidemics. MethodsData of confirmed monkeypox cases residing in this district were collected from the Disease Control and Prevention Information System of China. A retrospective descriptive epidemiological analysis was used to analyze the demographic, distributional and behavioral characteristics of the cases. ResultsThe first confirmed case of monkeypox was reported on July 5, 2023. Up to April 30, 2025, a total of 21 confirmed cases of monkeypox have been reported. All cases were male, with a mean age of (30.9±6.2) years. The highest proportion of cases(47.62%) was in the 30‒40 years age group. The majority were men who have sex with men (MSM) population (90.48%, 19/21). The results showed that 19.05% of cases were co-infected with HIV, and 19.05% had a history of syphilis infection. Within 21 days prior to symptom onset, 19 cases (90.48%) self-reported engaging in male-to-male sexual contact, among whom 10 cases (52.63%) reported having taken protective measures, while 9 cases (47.37%) did not take safety precautions. Thirteen cases (61.90%) had no travel history to areas with reported monkeypox cases during the 21 days before symptom onset. The predominant manifestation was exanthem (100%, 21/21), followed by fever (57.14%, 12/21) and lymphadenectasis (47.62%, 10/21). Among febrile cases, 50.00% (6/12) had low-grade fever (37.3‒38.0 ℃). All cases were identified through active medical consultation. The median interval from symptom onset to the first medical visit was 3 (2, 6) days, with a maximum interval of 14 days. The median interval from symptom onset to laboratory confirmation was 7 (5, 9) days. Six cases (28.57%) had two or more visits to the hospital, with bacterial infection being the primary initial diagnosis. ConclusionMonkeypox prevention and control efforts in a district of Chengdu City should prioritize MSM population and young and middle-aged adults aged 30 to <40 years. It is recommended to establish an integrated monkeypox epidemic prevention and control network by leveraging existing HIV/AIDS prevention and control network. Concurrently, accelerating the deployment of the national intelligent infectious disease monitoring and early warning front-end software will strengthen early detection capabilities and be beneficial for the overall effectiveness of epidemic prevention and control efforts.
