Spontaneous haemorrhage- Is imatinib the cause?
- Author:
Dhanya RAMACHANDRAN
1
;
Saravanan THANGAVELU
1
Author Information
1. Department of Medicine, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India
- Publication Type:Case Reports
- Keywords:
Adverse events;
complications;
bleeding;
tyrosine kinase-C inhibitor
- From:
Brunei International Medical Journal
2013;9(1):6-66
- CountryBrunei Darussalam
- Language:English
-
Abstract:
Imatinib, a tyrosine kinase-C protein inhibitor remains the first choice for the management of chronic
myeloid leukaemia (CML) since its introduction over a decade ago. Intracranial and gastrointestinal
haemorrhages have been previously reported in association with Imatinib therapy. We report the case
of a 47-yr-old man who was recently diagnosed with chronic phase of CML, that was complicated by a
spontaneous intramuscular haematoma in the left gluteal region after 10 days of treatment with
Imatinib. To the best of our knowledge, an intramuscular haemorrhage has not been described so far in
association with Imatinib therapy. Clinicians should be alert to the possibility of spontaneous haemor-
rhage at unusual sites in patients being treated with Imatinib.
- Full text:202606181347492411720139163.pdf
