Kikuchi-Fujimoto’s disease and scrub typhus: A rare association
- Author:
D. Rinuchitra
1
;
Jagadeeswaran Govindarajan
1
;
Saravanan THANGAVELU
1
;
Alamelu JAYARAMAN
2
Author Information
1. Department of Medicine, Institute of Medical Science and Research, Coimbatore, India
2. Department of Pathology, PSG Hospitals, Institute of Medical Science and Research, Coimbatore, India
- Publication Type:Case Reports
- Keywords:
Histiocytic necrotising lymphadenitis;
young male;
diagnosis;
anti-inflammatory agents;
scrub typhus
- From:
Brunei International Medical Journal
2012;8(5):271-274
- CountryBrunei Darussalam
- Language:English
-
Abstract:
Kikuchi-Fujimoto’s disease (KFD), histologically described as necrotising histiocytic lymphadenitis, is a
benign self-limiting disease though a few fatalities have been reported. It is uncommon outside Japan
and other Asiatic countries and thus lack of awareness among physicians may have led to its under-
diagnosis or misdiagnosis as lymphoma or tuberculosis. It has recently gained importance due to its
possible association with autoimmune disorders and viral infections especially Infectious Mononucleo-
sis. Here we report a young South Indian man with fever, upper respiratory tract infection and tender
cervical lymphadenopathy confirmed by biopsy to be KFD. He also had coexistent scrub typhus infec-
tion evident by positive markers during the course of illness, which became negative six weeks later.
Supportive management with non-steroidal anti-inflammatory agents has led to complete remission of
symptoms. Association between KFD and scrub typhus has not been previously reported.
- Full text:2026061716153788118201285274.pdf