Research advances in deep medullary vein lesions of the brain
10.19845/j.cnki.zfysjjbzz.2026.0064
- VernacularTitle:脑深髓静脉病变相关研究进展
- Author:
Zhifu LI
1
;
Xuejun XIE
1
Author Information
1. Department of Neurology， Affiliated Hospital of Chifeng University， Chifeng 024050， China
- Publication Type:Journal Article
- Keywords:
Deep medullary veins;
Venous collagenosis;
Susceptibility-weighted imaging;
Neurological disorders
- From:
Journal of Apoplexy and Nervous Diseases
2026;43(4):373-378
- CountryChina
- Language:Chinese
-
Abstract:
Deep medullary vein （DMV） lesions refer to the structural and functional abnormalities of the small venous system within the deep white matter under pathological conditions. Under normal physiological circumstances， DMV are responsible for venous drainage of deep white matter and clearance of metabolic waste. The pathogenesis of DMV lesions mainly involves luminal stenosis caused by collagen deposition in the venous wall， hemodynamic disturbances due to elevated venous pressure， functional impairment of the venous wall induced by inflammatory responses and cytokines， and microcirculatory disturbance caused by ischemia and hypoxia. Studies have shown that DMV lesions are extensively observed in various neurological disorders， including acute ischemic stroke， cerebral small vessel disease， multiple sclerosis， and Sturge-Weber syndrome， and are closely associated with the imaging manifestations， clinical progression， and prognosis of these diseases. However， despite the continuous improvement in the capability for DMV detection， the specific role of DMV in the pathogenesis of different diseases remains unclear. Further studies are needed to explore the role of DMV in pathophysiological processes and assess its clinical value as a target for early diagnosis and intervention， so as to facilitate the development of precision medicine.
- Full text:202606121454381174脑深髓静脉病变相关研究进展.pdf
