Linear and nonlinear electroencephalography characteristics during the ictal period of rapid eye movement sleep behavior disorder
10.19845/j.cnki.zfysjjbzz.2026.0056
- VernacularTitle:快速眼动睡眠行为障碍发作期脑电线性和非线性特征分析
- Author:
Zhijun QIU
1
;
Huaying TAO
1
Author Information
1. Department of Neurology， General Hospital of Tianjin Medical University， Tianjin 300052， China
- Publication Type:Journal Article
- Keywords:
Rapid eye movement sleep behavior disorder;
Electroencephalography power spectrum;
Approximate entropy;
Neurological pathway disorders
- From:
Journal of Apoplexy and Nervous Diseases
2026;43(4):327-331
- CountryChina
- Language:Chinese
-
Abstract:
Objective Rapid eye movement sleep behavior disorder（RBD） is a common sleep disorder in the elderly， and this study aims to investigate the activity of cerebral cortex based on the changes in electroencephalography （EEG） power spectrum and the difference in approximate entropy during the ictal period of RBD. Methods A total of 35 patients with idiopathic RBD who received video polysomnography monitoring were enrolled as RBD group， and 25 normal volunteers matched for age were enrolled as control group.REM EEG results with fewer artifacts was selected for both groups， and the RBD group had an increase in mandibular electromyographic activity or dream-enacting behaviors. The leads containing artifacts were excluded， and finally O1 （or O2 alternative） leads with relatively little interference were selected. After pretreatment， Fourier transform was performed for EEG data from both groups to calculate the absolute power and relative power ratio of EEG in five different frequency bands， i.e.， δ （0.5-3 Hz）， θ （4-7 Hz）， α （8-13 Hz）， β （14-30 Hz）， and γ （30-35 Hz）. The normal distribution of power values in each frequency band was tested for both groups， and the t-test was used for comparison. Approximate entropy was calculated for EEG in both two groups， and the t-test was used for comparison. Results The θ band was the dominant frequency band of REM EEG in both the control group and the RBD group. Compared with the control group， the RBD group had a significant increase in the absolute power of fast-wave activity on REM α band and significant reductions in δ/α and θ/α relative power ratios. There was a significant difference in EEG ApEn value between the control group and the RBD group （P<0.05）， and the RBD group had a higher ApEn value during REM sleep than the NC group， with a significant difference in EEG ApEn value during the phase of dream-enacting behaviors. Conclusion In the RBD group， there are significant increases in the absolute power and nonlinear approximate entropy of fast-wave activity on REM α band during the ictal period of REM， which reflects the hyperactive functional changes of cerebral cortex during the ictal period of RBD， and the involvement of cerebral cortex in RBD neural pathway disorders is an important supplement to the current theory. Moderate inhibition of cerebral cortex hyperactivity is of great significance for the treatment of RBD.
- Full text:2026061214100230119快速眼动睡眠行为障碍发作期脑电线性和非线性特征分析.pdf
