Intractable epilepsy caused by temporal lobe encephaloceles： A case report

VernacularTitle:颞叶脑膨出所致难治性癫痫1例报告并文献复习
Author: Xiaoyan LIU ¹ ; Ling LIU ¹
Author Information

1. Department of Neurology， West China Hospital， Sichuan University， Chengdu 610041， China
Publication Type:Journal Article
Keywords: Temporal lobe encephaloceles; Temporal lobe epilepsy; Intractable epilepsy
From: Journal of Apoplexy and Nervous Diseases 2026;43(3):269-274
CountryChina
Language:Chinese
Abstract: This article analyzes the clinical features， diagnosis， and treatment of temporal lobe encephaloceles （TEs）， a rare and frequently underdiagnosed etiology of drug-resistant temporal lobe epilepsy （DR-TLE）. Based on the data of a patient with a six-year history of DR-TLE， this patient was diagnosed with left TEs after cranial MRI， PET-CT， and ictal video-electroencephalography and then underwent surgical resection of the lesion. The patient achieved effective seizure control after surgery， with complete freedom from seizures after follow-up for 5 years. With reference to this case and the literature review， TEs is a rare cause of DR-TLE and is easily missed clinically， which warrants vigilance. Radiological examinations such as high-resolution three-dimensional cranial MRI and PET are of great importance for the confirmed diagnosis of this disease. For such patients， surgical treatment can achieve significant and sustained therapeutic outcomes.