Diagnostic & Therapeutic Challenges of Actinomycosis: A Benign Speck Masquerading as a Soft Tissue Malignancy
- Author:
Amirul Ashraf Abdul Kadir
1
;
Boay Heong Eyrique Goh
1
;
Kok Keat Tee
1
;
Joon Hi Tham
2
;
Gerrarde Paul Aaron
1
Author Information
- Publication Type:Case Reports
- MeSH: Actinomycosis.
- From: International e-Journal of Science, Medicine and Education 2025;19(2):37-42
- CountryMalaysia
- Language:English
- Abstract: Diagnostic & Therapeutic Challenges of Actinomycosis: A Benign Speck Masquerading as a Soft Tissue Malignancy:Actinomycosis is a chronic infection caused by filamentous gram-positive anaerobes, typically presenting in cervicofacial regions. We report a rare case involving the lower limb of an immunocompetent male, initially suspected to have soft tissue sarcoma based on imaging. The diagnosis was confirmed histologically with characteristic sulfur granules and the Splendore-Hoeppli phenomenon. Despite antibiotic therapy, non-compliancy led to disease progression and necessitated a below-knee amputation. This case emphasises the importance of early diagnosis, patient compliance, and a multidisciplinary approach in managing rare infections mimicking malignancies.
- Full text:2026061016121301952Diagnostic and Therapeutic Challenges of Actinomycosis.pdf
