Research progress on effects of environmental endocrine disruptors on pubertal timing in children and adolescents
10.16835/j.cnki.1000-9817.2026154
- VernacularTitle:环境内分泌干扰物影响儿童青少年青春发动时相的研究进展
- Author:
WANG Jie, LUO Ling, TAO Fangbiao, YAN Shuangqin
1
Author Information
1. Department of Maternal, Child & Adolescent Health, School of Public Health, Anhui Medical University, Hefei 230032, Anhui Province, China
- Publication Type:Journal Article
- Keywords:
Endocrine disruptors;Adolescent development;Child;Adolescent
- From:
Chinese Journal of School Health
2026;47(5):751-755
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:In order to explore the influence of different environmental endocrine disruptors (EEDs) on the onset of youth in children and adolescents, the study introduces the advance trend of the onset of youth in children and adolescents at home and abroad, and the influence of EEDs, such as bisphenol A, organophosphate esters, phthalic acid esters, per and polyfluoroalkyl substances, which children and adolescents often contact on the onset of youth. The related mechanisms are expounded from the aspects of direct interference of EEDs on neuroendocrine axis, hormone simulation and antagonism mediated by receptors, epigenetic programming changes, indirect pathways mediated by obesity and inflammation, etc., in order to provide scientific basis for formulating preventive measures for abnormal puberty onset of children and adolescents in EEDs exposure and promote their health.
- Full text:2026060910172751117汪洁.pdf