Impact of infusion of red blood cell suspension at different perioperative periods in patients with valvular heart disease: A propensity score matching study
- VernacularTitle:围术期不同时间段输注悬浮红细胞对心脏瓣膜病患者影响的倾向性评分匹配研究
- Author:
Shan XU
1
;
Bo FU
2
;
Ao WEI
3
;
Qian ZHANG
4
;
Yaqing CAO
1
;
Nan JIANG
2
;
Zhigang GUO
2
Author Information
1. Department of Blood Transfusion, Tianjin Chest Hospital, Tianjin, 300222, P. R. China
2. Department of Cardiovascular Surgery, Tianjin Chest Hospital, Tianjin, 300222, P. R. China
3. Department of Cardiology, Tianjin Chest Hospital, Tianjin, 300222, P. R. China
4. Department of Clinical Lab, Tianjin Chest Hospital, Tianjin, 300222, P. R. China
- Publication Type:Journal Article
- Keywords:
Perioperative period;
red cell suspension;
valvular heart disease;
transfusion
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2026;33(05):772-777
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of red blood cell suspension infusion across various perioperative periods on patients with valvular heart disease. Methods The patients with valvular heart disease admitted to Tianjin Chest Hospital from 2018 to 2020 were selected. Based on the timing of perioperative red cell suspension infusion, patients were categorized into three groups: a group 1 receiving intraoperative red cell suspension infusion, a group 2 receiving red cell suspension infusion within 24 hours after entering the ICU, and a group 3 receiving red cell suspension infusion at both time points. The laboratory results, perioperative blood component infusion volume, and other relevant parameters were retrospectively analyzed. After propensity score matching, the differences in different variables among the three groups were compared. Results After propensity score matching, 102 patients were enrolled, including 52 males and 50 females, with an average age of (61.74±10.58) years. There were 34 patients in each group. The preoperative hemoglobin (Hb) value of the group 2 was significantly higher than that of the group 1 and the group 3, and the amount of red cell suspension and autoblood transfusion was the lowest (P<0.05). Group 1 had the highest postoperative Hb, as well as the highest Hb and hematocrit (HCT) levels within 24 hours post-surgery (P<0.05). The group 1 had the lowest plasma, platelet and cryoprecipitate infusion volumes, and the shortest cardiopulmonary bypass time, aortic occlusion time, postoperative ICU stay and hospital stay, and the least blood loss and total drainage volume (P<0.05). The difference between postoperative and preoperative Hb (△Hb1) was highest in group 1 (P<0.05). Conclusion For patients with valvular heart disease, intraoperative-only infusion of red blood cell suspension is associated with a better prognosis at discharge and during follow-up.
