Analysis on clinical features of 23cases of chlorfenapyr poisoning
10.3760/cma.j.cn121094-20240325-00115
- VernacularTitle:23例虫螨腈中毒临床特征分析
- Author:
Yan PU
1
;
Xinghui JIANG
1
;
Xianghu LI
1
;
Qunmei YAO
1
Author Information
1. 云南省楚雄彝族自治州人民医院急诊科，楚雄 675000
- Publication Type:Journal Article
- Keywords:
Chlorfenapyr;
Poisoning;
Clinical features
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2025;43(6):462-465
- CountryChina
- Language:Chinese
-
Abstract:
Chlorfenapyr is a novel pyrrole insecticide widely used in agricultural production. Due to its broad insecticidal activity, low resistance, rapid action, and long-lasting effects, its use has been increasing. In the past three years, there have been incidents of imidacloprid poisoning in China. We reviewed and analyzed the clinical characteristics of patients treated for chlorfenapyr poisoning at the People's Hospital of Chuxiong Yi Autonomous Prefecture from November 2019 to November 2023. The 23 patients included 15 males and 8 females, with ages ranging from 11 to 71 years. Twenty-two cases were due to gastrointestinal exposure, and one case was due to skin or respiratory tract exposure. Clinical symptoms included nausea, vomiting, fever, profuse sweating, and altered consciousness. Laboratory tests showed elevated levels of aspartate aminotransferase and creatine kinase. There was no specific antidote available, and 10 patients died after treatment, resulting in a mortality rate of 43.5%. Among the deceased, a higher proportion experienced fever, profuse sweating, altered consciousness, and generalized muscle stiffness.
