Report on an occupational acute malononitrile poisoning accident
10.3760/cma.j.cn121094-20240205-00047
- VernacularTitle:一起职业性急性丙二腈中毒事故报告
- Author:
Yanmei SHEN
1
;
Jianhua XIAO
1
Author Information
1. 惠州市职业病防治院职业卫生管理科，惠州 516008
- Publication Type:Journal Article
- Keywords:
Poisoning;
Gas;
Malononitrile;
Hypoxia;
Metabolic acidosis;
Pharmaceutical factory
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2025;43(5):389-391
- CountryChina
- Language:Chinese
-
Abstract:
This article reports on an occupational acute chemical poisoning incident that occurred in a pharmaceutical company in Huizhou, Guangdong Province in August 2023. After investigating the input materials, protective facilities, personal protective equipment, and emergency rescue supplies at the accident site, the causes of the accident and clinical data of the poisoned patients were analyzed. The main manifestations of patient poisoning are hypoxia (coma, low finger pulse oxygen, skin cyanosis) and metabolic acidosis (low pH and increased lactate). Through comprehensive analysis, it is determined that this incident is an occupational acute malononitrile poisoning incident. The main cause of the incident was the leakage of acetonitrile at the scene, which was caused by workers violating operating procedures and failing to take labor protection measures.
