Interpretation of the 2024 European guidelines on the diagnosis and management of pediatric eosinophilic esophagitis
10.3760/cma.issn.j.cn311367-20240924-00363
- VernacularTitle:2024版欧洲儿童嗜酸细胞性食管炎诊治指南解读
- Author:
Weimei HE
1
;
Chenmei ZHANG
;
Jiani SHAN
Author Information
1. 浙江大学医学院附属儿童医院邵逸夫国际医学中心 国家儿童健康与疾病临床医学研究中心，杭州 310052
- Publication Type:Journal Article
- Keywords:
Child;
Eosinophilic esophagitis;
Esophagitis;
Guidelines;
Expert consensus;
Follow-up
- From:
Chinese Journal of Digestion
2025;45(3):145-155
- CountryChina
- Language:Chinese
-
Abstract:
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease driven by immune mechanisms, characterized by abnormal eosinophilic infiltration of the esophageal epithelium. EoE′s pathogenesis is closely associated with food allergens, and clinical manifestations primarily include dysphagia, food impaction, and children patients may also have growth restriction. The European Society for Paediatric Gastroenterology, Hepatology, and Nutrition first published guidelines for the management of pediatric EoE in 2014. With increasing understanding of the disease mechanisms and treatment responses, the 2024 guidelines have comprehensively updated the diagnostic and therapeutic strategies.This paper provides a systematic interpretation of the 2024 guidelines, focusing on the revised diagnostic criteria, optimization of dietary therapy, and improved management strategies for esophageal strictures. Furthermore, a comparison of the 2014 and 2024 guidelines highlights significant advancements in EoE management over the past decade and their implications for clinical practice.
