Progress of individualized precision therapy for peritoneal metastasis in gastric cancer
10.3760/cma.j.cn112139-20250313-00127
- VernacularTitle:胃癌腹膜转移的个体化精准治疗进展
- Author:
Junhua ZHAO
1
;
Yuqing YANG
1
;
Rui MA
1
;
Chengzhi ZHANG
1
;
Zhengchao HONG
1
;
Zhenning WANG
1
Author Information
1. 中国医科大学附属第一医院胃肠肿瘤外科，沈阳 110001
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Neoplasm metastasis;
Peritoneal metastasis;
Precision medicine
- From:
Chinese Journal of Surgery
2025;63(7):552-557
- CountryChina
- Language:Chinese
-
Abstract:
Peritoneal metastasis represents the most aggressive form of gastric cancer metastasis and serves as a primary contributor to poor prognosis. Conventional therapeutic approaches offer limited survival benefits, making the development of novel treatment strategies an urgent medical priority. With advancements in molecular medicine and sociomedical sciences, contemporary cancer management is evolving towards individualized precision medicine. This transition has given rise to a plethora of innovative therapeutic strategies, including molecular typing-driven targeted therapy, immunotherapy, and locally targeted technology. These strategies emphasize the construction of a precise and individualized therapeutic framework through the integration of genomics, imaging genomics, and artificial intelligence-assisted decision-making, which promotes the continuous improvement of treatment strategies for peritoneal metastasis of gastric cancer. This article provides a comprehensive analysis of the prevailing individualized treatment modalities from the standpoint of precision medicine, offering novel perspectives on the management of peritoneal metastasis in gastric cancer.
