Progress in the application of minimal residual lesion detection in the precision diagnosis and treatment of esophageal cancer
10.3760/cma.j.cn112139-20241116-00515
- VernacularTitle:微小残留病灶检测在食管癌精准诊治中的应用进展
- Author:
Xu ZHOU
1
;
Chunji CHEN
1
;
Xufeng GUO
1
;
Zhigang LI
1
Author Information
1. 上海市胸科医院 上海交通大学医学院附属胸科医院胸外科，上海 200030
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Sequence analysis, DNA;
Esophageal cancer;
Minimal residual disease;
Circulating tumor DNA
- From:
Chinese Journal of Surgery
2025;63(5):448-452
- CountryChina
- Language:Chinese
-
Abstract:
The detection of minimal residual lesions represented by circulating tumor DNA can detect residual cancer lesions that cannot be displayed by traditional imaging in advance. The positive status and dynamic changes are closely related to the prognosis evaluation of various solid tumors, the effectiveness of neoadjuvant therapy, the prediction of postoperative recurrence risk, and the precise implementation of adjuvant therapy. This article summarizes the advantages and challenges faced by the application of circulating tumor DNA testing in individualized multidisciplinary diagnosis and treatment of esophageal cancer, in order to better carry out precise diagnosis and treatment of esophageal cancer under the guidance of minimal residual lesion detection.
