Advances in the role of maternal microbial dysbiosis in the pathogenesis of preeclampsia
10.3760/cma.j.cn113903-20241125-00783
- VernacularTitle:母体微生态失调在子痫前期发病机制中的作用研究进展
- Author:
Shaoqi CHEN
1
;
Yin ZHAO
Author Information
1. 华中科技大学同济医学院附属协和医院妇产科，武汉 430022
- Publication Type:Journal Article
- Keywords:
Preeclampsia;
Maternal microbiome;
Pathophysiology mechanism
- From:
Chinese Journal of Perinatal Medicine
2025;28(5):431-436
- CountryChina
- Language:Chinese
-
Abstract:
During pregnancy, physiological changes occur in the maternal microbiome. Dysbiosis of the maternal microbial community and the production of abnormal derivative metabolites participate in the occurrence and development of preeclampsia through multiple mechanisms. This article reviews the distribution of maternal microbiota, microbial dysbiosis, and the specific mechanisms by which they participate in the pathogenesis of preeclampsia.
