Health economics evaluation of core interventions in early essential newborn care
10.3760/cma.j.cn113903-20240201-00057
- VernacularTitle:新生儿早期基本保健核心干预措施的卫生经济学评价
- Author:
Huanqing HU
1
;
Tao XU
1
Author Information
1. 国家卫生健康委妇幼健康中心，北京 100089
- Publication Type:Journal Article
- Keywords:
Economics evaluation;
Early essential newborn care;
Kangaroo mother care;
Neonatal resuscitation
- From:
Chinese Journal of Perinatal Medicine
2025;28(3):219-225
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the status of health economics evaluation studies on the core interventions in early essential newborn care (EENC).Methods:Relevant articles were retrieved from Chinese databases including CNKI, Wanfang Data, Yiigle, and VIP Chinese Journals using keywords in Chinese, including "early neonatal care," "resuscitation of birth asphyxia," "kangaroo mother care (KMC)" "neonatal vitamin K," "health economics," and "cost," "benefit," or "effect" and from databases such as PubMed, Embase, Springer, Google Scholar, and Web of Science using keywords such as "economic evaluation," "assessing," "cost," "cost-effective," "effective," "effect," "kangaroo mother care or KMC," "resuscitation of neonatal asphyxia/help baby breathe/neonatal asphyxia," "injection of vitamin K 1/intramuscular vitamin K 1 neonatal/newborns" and other core interventions in EENC. The retrieved literature was screened. The quality of the included articles was evaluated according to the Quality of Health Economic Studies (QHES) instrument. The research objects, types, main indicators, and results were summarized. Results:A total of 16 articles were finally included in this study, including nine related to KMC (of which two had no real-world data and were only statistical model studies), four related to neonatal resuscitation (all without real-world data), and three related to intramuscular injection of vitamin K 1 (of which one had no real-world data). No articles on other core interventions in EENC were retrieved. There were eight articles based on the analysis of previous health system or hospital data, four using a randomized controlled trial, two retrospective studies based on convenience sampling, and two comparing the effects before and after a project. Only two studies used the data from 2018 onwards. The 16 included articles were evaluated according to QHES and only three were rated as excellent. Regarding health economics evaluation of intervention measures, the included studies believed implementing KMC was more effective and less costly. Full resuscitation, selective resuscitation, and intramuscular injection of vitamin K 1 for newborns were cost-effective intervention measures. Conclusions:There are few health economics evaluation studies on EENC intervention measures, and the evidence of the studies is limited. In the future, the effects and health economic benefits of interventions in EENC in China can be predicted and analyzed by conducting high-quality randomized controlled studies or pre- and post-intervention comparative studies or using statistical methods such as establishing decision tree models to analyze the past data of hospital cases or from the health system.
