Effects of hyperbaric oxygen combined with warming needle moxibustion on physical function, joint range of motion, and inflammatory factors in patients with ankylosing spondylitis
10.3760/cma.j.cn311847-20191204-00352
- VernacularTitle:高压氧联合温针灸治疗对强直性脊柱炎患者躯体功能、关节活动度及炎性因子水平的影响
- Author:
Ge YAN
1
;
Jihong YAO
;
Yanmei LI
;
Peng QIAO
;
Shuhua LIU
;
Li MA
;
Li CHEN
;
Fengde JING
Author Information
1. 264001 山东省烟台，烟台市烟台山医院中医科
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Warming needle moxibustion;
Ankylosing spondylitis;
Physical function;
Joint range of motion;
Inflammatory factor
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2020;27(6):687-690
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of hyperbaric oxygen (HBO) combined with warming needle moxibustion on the improvement of physical function, joint range of motion, and inflammatory factors in patients with ankylosing spondylitis (AS).Methods:A total of 128 AS patients admitted to the Department of Traditional Chinese Medicine of Yantai Mountain Hospital from June 2017 to December 2018 were selected as the study objects and randomly divided into control group ( n=64) and observation group ( n=64). The control group was given conventional treatment combined with warming needle moxibustion, and the observation group was given HBO on the basis of the treatments in the control group. The physical function of the patients was assessed by using the Bath Ankylosing Spondylitis Functional Index (BASFI), and the visual analogue scale (VAS) score was included to jointly evaluate the lumbosacral back pain and joint pain. The Bath Ankylosing Spondylitis Metrology Index (BASMI) was used to assess joint range of motion, and the enzyme linked immunosorbent assay (ELISA) was used to detect the changes in inflammatory factor levels before and after treatment. Results:After treatment, the physical function and the severity of pain of the patients in both groups were significantly improved compared with those before treatment ( P<0.05), and the BASFI and VAS scores of the observation group were significantly lower than those of the control group ( P<0.05). Meanwhile, the test results of thoracic range of motion, Schober test, fingertips to floor distance, lumbar lateral flexion, extension of the lumbar spine, and occiput to wall distance were all significantly improved, and the improvements of the above tests in the observation group wee all greater than those in the control group, all with statistically significant differences ( P<0.05). The levels of inflammatory factors, such as erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and tumor necrosis factor-α (TNF-α) significantly decreased ( P<0.05), moreover, the levels of those factors in the observation group were all lower than those in the control group, all with statistically significant differences ( P<0.05). The total effective rate in the observation group (92.19%) was higher than that in the control group (78.13%), and the difference was statistically significant ( P<0.05). Conclusion:Hyperbaric oxygen combined with warming needle moxibustion can significantly improve the curative effect on AS patients by effectively reducing the levels of inflammatory factors, decreasing the pain, and improving the physical function and joint range of motion, which is worthy of clinical promotion and application.
