Research progress on factors contributing to postoperative pancreatic fistula after pancreatoduodenectomy
- VernacularTitle:胰十二指肠切除术后胰瘘发生危险因素的研究进展
- Author:
Haohao DING
1
;
Niu DAI
1
;
Pan ZHAO
1
;
He BAI
1
;
Yuxin TENG
1
;
Xiao LI
1
;
Zhengcai LIU
1
;
Shuqiang YUE
1
Author Information
- Publication Type:Journal Article
- Keywords: Pancreaticoduodenectomy; Pancreatic fistula; Pancreatic cancer; Influencing factors
- From: Chinese Journal of Hepatobiliary Surgery 2025;31(8):637-640
- CountryChina
- Language:Chinese
- Abstract: Pancreaticoduodenectomy (PD) stands as one of the most challenging landmark procedures in general surgery. Postoperative pancreatic fistula (POPF), a common complication following PD, predisposes patients to secondary pathologies and remains difficult to avoid. Reducing its incidence and mitigating its impact have become focal points in pancreatic surgical research. This article comprehensively reviews domestic and international literature to systematically analyze key factors influencing POPF across three phases: preoperative, intraoperative, and postoperative management. By gaining deeper insights into the pathogenesis of POPF, this review aims to enhance clinical understanding among healthcare professionals, facilitate the implementation of preventive strategies, and offer novel perspectives for minimizing postoperative fistula risks.
