Advances in conversion therapy for unresectable hepatocellular carcinoma
10.3760/cma.j.cn113884-20250224-00058
- VernacularTitle:不可切除肝细胞癌转化治疗的研究进展
- Author:
Ke YU
1
;
Jiajia JIA
;
Ying SHA
;
Yufan TANG
;
Baiquan ZHOU
;
Bingbing WEN
;
Luyao LI
;
Jixiang LIU
;
Ruifang FAN
Author Information
1. 甘肃中医药大学第一临床医学院，兰州 730030
- Publication Type:Journal Article
- Keywords:
Carcinoma, hepatocellular;
Conversion therapy;
Targeted therapy;
Immunotherapy;
Interventional therapy;
Radiotherapy
- From:
Chinese Journal of Hepatobiliary Surgery
2025;31(9):706-711
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. Surgical resection remains the preferred treatment modality, offering the potential for cure. However, over half of HCC patients present as intermediate to advanced stages at diagnosis, with multiple factors precluding surgical resection. Conversion therapy represents an important treatment strategy by enabling tumor downstaging, offering future resectability for patients with intermediate-to-advanced HCC who are initially unresectable. This article reviews the relevant concepts and research progress in conversion therapy for HCC.
