Research progress of the pathogenesis of androgenic alopecia
10.3760/cma.j.cn114453-20231106-00191
- VernacularTitle:雄激素性脱发发病机制的研究进展
- Author:
Changjiang ZHAO
1
;
Yufei LI
1
;
Hua JIANG
1
Author Information
1. 同济大学附属东方医院整形外科，上海 200120
- Publication Type:Journal Article
- Keywords:
Androgens;
Alopecia;
Dihydrotestosterone;
Etiology
- From:
Chinese Journal of Plastic Surgery
2025;41(3):328-332
- CountryChina
- Language:Chinese
-
Abstract:
Androgenic alopecia (AGA) stands as a prevalent and challenging dermatological condition in clinical practice. Its pathogenesis is complex and the condition is prone to recurrence, which seriously affects the physical and mental health of patients. This review synthesized recent advancements in understanding the multifaceted mechanisms underlying AGA progression. It delineated the intricate interplay among genetic predispositions, hormonal influences, cytokine-mediated regulations, molecular pathway activations, and alterations in the hair follicle microenvironment. By elucidating these diverse factors and their interactions, this article aimed to provide a theoretical basis and reference for new targets of action for the clinical treatment of AGA.
