Progress in the classification of oncocytic and chromophobe renal tumors
10.3760/cma.j.cn115355-20250127-00058
- VernacularTitle:嗜酸和嫌色性肾肿瘤分类进展
- Author:
Manxiang CHEN
1
;
Jie ZUO
;
Shan ZHENG
Author Information
1. 国家癌症中心 中国医学科学院北京协和医学院肿瘤医院病理科，北京 100021
- Publication Type:Journal Article
- Keywords:
Kidney neoplasms;
Oxyphil cells;
Immunohistochemistry;
Pathology, clinical
- From:
Cancer Research and Clinic
2025;37(7):553-556
- CountryChina
- Language:Chinese
-
Abstract:
The 2022 World Health Organization classification of renal cell tumors classifies oncocytoma, chromophobe cell carcinoma, and the intermediate forms between the both as oncocytic and chromophobe renal tumors. The intermediate tumors are named other oncocytic tumors of the kidney including oncocytic renal neoplasms of low malignant potential-not otherwise specified, eosinophilic vacuolated tumor and low-grade oncocytic tumor. These tumors are more common in the elderly and they usually show benign or low-invasive clinical courses. Additionally, molecular features provide certain assistance in typing. This paper reviews the evolution of name and summarizes the clinicopathological characteristics, molecular characteristics and the differential diagnosis of oncocytic and chromophobe renal tumors.
