Pathological mechanisms, risk factors, and preventive strategies of cardiac surgery-associated acute kidney injury

VernacularTitle:心脏手术相关急性肾损伤的病理机制、危险因素及预防策略
Author: Yikai HE ¹ ; Shuyue SHEN ¹ ; Huipeng GE ¹ ; Linlin ZHANG ¹ ; Xiangcheng XIAO ¹
Author Information

1. 中南大学湘雅医院肾内科，长沙　410008
Publication Type:Journal Article
Keywords: Acute kidney injury; Cardiac surgery; Risk factors; Biomarker
From: Journal of Chinese Physician 2025;27(9):1430-1436
CountryChina
Language:Chinese
Abstract: Acute Kidney Injury (AKI) is a common and severe complication after cardiac surgery. The pathogenesis of cardiac surgery-associated AKI (CSA-AKI) is complex, and it is associated with increased patient mortality and poor renal prognosis. To identify high-risk patients as early as possible, numerous clinical studies have explored perioperative risk factors and developed a variety of biomarkers with good diagnostic capabilities. Currently, multiple prediction models for AKI after cardiac surgery have been developed internationally; however, there is no effective treatment for CSA-AKI. Therefore, implementing reasonable and comprehensive preventive strategies is crucial. In addition, the clinical application of some interventions is controversial, which means more research and exploration are needed to make more informed decisions regarding the prevention and treatment of CSA-AKI.