Clinical analysis and regional experience of extracorporeal membrane oxygenation in the treatment of critically ill pregnant and postpartum women in Bao′an district, Shenzhen
10.3760/cma.j.cn431274-20250725-00990
- VernacularTitle:深圳市宝安区危重孕产妇ECMO救治的临床分析与区域性经验
- Author:
Youmei CHEN
1
;
Shengyuan SU
;
Jianxin ZHEN
;
Chenhong WANG
;
Quanfu ZHANG
Author Information
1. 香港中文大学妇女儿童医学中心(深圳)妇产科，深圳 518100
- Publication Type:Journal Article
- Keywords:
Extracorporeal membrane oxygenation;
Obstetric critical illness;
Regional network
- From:
Journal of Chinese Physician
2025;27(9):1294-1299
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the application indications, clinical characteristics and influencing factors of extracorporeal membrane oxygenation (ECMO) in the treatment of critically ill pregnant and postpartum women in Bao′an district, Shenzhen, and summarize regional experience.Methods:A retrospective analysis was conducted on 5 cases of pregnant and postpartum women who received ECMO treatment at the CUHK Women′s and Children′s Medical Centre (Shenzhen) and the Shenzhen Bao′an People′s Hospital from 2020 to 2024. Baseline characteristics, ECMO parameters, complications and maternal-infant outcomes of the patients were collected.Results:The patients′ age was 29(24, 36) years old, gestational age was 39(31, 39) weeks, and ECMO maintenance time was 8(4, 8) days. ECMO indications included 2 cases of cardiac arrest, 1 case of respiratory and circulatory failure, 1 case of cardiogenic shock, and 1 case of acute respiratory distress syndrome. There were 4 cases of veno-arterial (VA)-ECMO and 1 case of veno-venous (VV)-ECMO. Complications included 3 cases of bleeding, 4 cases of acute renal failure, 2 cases of thrombosis, and 2 cases of infection. Both maternal and infant survival were 3 cases. Successful cases benefited from the multidisciplinary rapid response team and regional transportation cooperation, while failed cases were mostly accompanied by severe bleeding and disseminated intravascular coagulation.Conclusions:ECMO improves the success rate of treating critically ill pregnant and postpartum women in Bao′an District. Amniotic fluid embolism and severe pulmonary hypertension are the main indications. Regional multidisciplinary cooperation, accurate initiation timing and individualized anticoagulation management are the keys. It is recommended to establish a national ECMO registration system for pregnant and postpartum women to optimize treatment strategies and improve maternal and infant prognosis.
