Impact of non-diabetic postoperative hyperglycemia on complications after anterior mediastinal tumor resection via lateral thoracic approach single-port thoracoscopy
10.3760/cma.j.cn431274-20240723-01132
- VernacularTitle:非糖尿病性术后高血糖对侧胸入路单孔胸腔镜前纵隔肿瘤切除术后并发症的影响
- Author:
Yan YANG
1
;
Yang YANG
1
;
Qinqin BAO
1
;
Feng SHAO
1
;
Qiulu ZHU
1
Author Information
1. 南京脑科医院（南京市胸科医院）胸外科，南京 210029
- Publication Type:Journal Article
- Keywords:
Mediastinal neoplasms;
Thoracoscopy;
Non-diabetic hyperglycemia;
Postoperative complications
- From:
Journal of Chinese Physician
2025;27(8):1208-1212
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the occurrence of non-diabetic hyperglycemia after anterior mediastinal tumor resection via lateral thoracic approach single-port thoracoscopy and its impact on postoperative complications.Methods:The medical records of 182 anterior mediastinal tumors admitted to the Nanjing Brain Hospital (Nanjing Chest Hospital) from January 2022 to March 2024 were retrospectively analyzed. All patients underwent anterior mediastinal tumor resection via lateral thoracic approach single-port thoracoscopy. They were divided into the hyperglycemia group ( n=54) and non-hyperglycemia group ( n=128) according to the occurrence of postoperative non-diabetic hyperglycemia. The postoperative complications were compared between the two groups. Patients with any complication showing statistically significant differences between the two groups were included in the complication group, and the remaining patients were included in the non-complication group. Binary logistic regression model was used to analyze the risk factors for postoperative complications in patients undergoing anterior mediastinal tumor resection via lateral thoracic approach single-port thoracoscopy. Results:The incidences of postoperative pain, wound fat liquefaction, wound infection, and pulmonary infection in the hyperglycemia group were significantly higher than those in the non-hyperglycemia group (all P<0.05). There were statistically significant differences in age, history of hypertension, triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), operation time, and postoperative hyperglycemia between the complication group and non-complication group (all P<0.05). Multivariate logistic regression analysis showed that age, history of hypertension, operation time, and postoperative hyperglycemia were independent risk factors for postoperative pain/wound fat liquefaction/wound infection/pulmonary infection in patients undergoing anterior mediastinal tumor resection via lateral thoracic approach single-port thoracoscopy (all P<0.05). Conclusions:Non-diabetic postoperative hyperglycemia can increase the risk of postoperative pain/wound fat liquefaction/wound infection/pulmonary infection in patients undergoing anterior mediastinal tumor resection via lateral thoracic approach single-port thoracoscopy, and it is an independent risk factor for the above postoperative complications.
