Predict value of tumor burden score combined with preoperative controlling nutritional status score on prognosis of patients with hepatocellular carcinoma after radical hepatectomy
10.3760/cma.j.cn113855-20240217-00123
- VernacularTitle:肿瘤负荷评分联合术前控制营养状态评分对肝细胞癌患者根治性切除术后预后的预测价值
- Author:
Xingbo WEI
1
;
Yifan ZHI
;
Liancai WANG
;
Dongxiao LI
;
Erwei XIAO
;
Deyu LI
Author Information
1. 河南大学人民医院肝胆胰腺外科，郑州 450003
- Publication Type:Journal Article
- Keywords:
Carcinoma,hepatocellular;
Hepatectomy;
Tumor burden score;
Controlling nutritional status score;
Prognosis
- From:
Chinese Journal of General Surgery
2024;39(12):941-946
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of tumor burden score (TBS)combined with preoperative control nutritional status(COUNT)score on prognosis of hepatocellular carcinoma patients after radical hepatectomy.Methods:The clinical and follow-up data of 165 HCC patients who underwent radical hepatectomy at People's Hospital,Henan University from Jan 2017 to Dec 2020 were retrospectively analyzed.Receiver operating characteristic (ROC) was used to evaluate the prognostic efficacy of TBS-COUNT score.Results:The median follow-up time was 17.0 months . The area under curve (AUC) of TBS-COUNT score for predicting 3-year postoperative survival and recurrence rate of HCC patients was 0.802 and 0.771, respectively ( P<0.05). The 1-,and 3-year cumulative survival rates in low-risk and high-risk groups were 98.65%, 71.62% and 82.42%, 47.76% respectively (all P<0.05). The 1-,and 3-year recurrence free survival rates were 87.84%, 25.68% and 42.86%, 4.40% in the low-risk group and the high-risk group, respectively (all P<0.05). Multivariate COX regression analysis showed that TBS-COUNT score is an independent risk factor for post-operative OS ( HR=2.14,95% CI: 1.04-4.42, P=0.040) and RFS ( HR=2.16,95% CI: 1.07-4.35, P=0.032) in HCC patients. Conclusion:TBS-COUNT score is an effective predictor of prognosis of hepatocellular carcinoma patients after radical resection.
