Recent advance in application of neuroimaging and electrophysiological techniques in diagnosis and prognosis evaluation of disorders of consciousness
10.3760/cma.j.cn115354-20240713-00412
- VernacularTitle:神经影像及电生理技术在意识障碍诊断、预后评估中的应用研究进展
- Author:
Jingjing LI
1
;
Shenghua CUI
1
;
Yongshi LIAO
1
Author Information
1. 南华大学附属第二医院神经外科,衡阳 421001
- Publication Type:Journal Article
- Keywords:
Disorders of consciousness;
Neuroimaging;
Neurophysiology
- From:
Chinese Journal of Neuromedicine
2025;24(5):465-471
- CountryChina
- Language:Chinese
-
Abstract:
Standardized clinical behavioral assessment remains the cornerstone for diagnosing disorders of consciousness (DoC). Nevertheless, mounting evidences underscore the substantial risk of misdiagnosis associated with exclusive reliance on behavioral evaluations. In contemporary neuroscience research, advanced neuroimaging and electrophysiological methodologies have emerged as powerful tools; these techniques not only enable in-depth characterization of the dynamic alterations in brain structure and function among DoC patients but also furnish critical insights for clinical decision-making, including accurate diagnosis, prognosis, and tailored therapeutic strategies. This review synthesizes the recent advance in applying neuroimaging and electrophysiological approaches in DoC diagnosis and prognosis evaluation, and discusses its technical advantages, clinical application scenarios and limitations, in order to provide new ideas and methods for DoC diagnosis and prognosis evaluation.