Recent advances in neural mechanisms, diagnosis and treatment of akinetic mutism
10.3760/cma.j.cn115354-20241211-00780
- VernacularTitle:运动不能性缄默症的神经机制及诊疗研究进展
- Author:
Kaisi REN
1
;
Shuchang ZHONG
1
;
Li ZHANG
1
;
Xiangming YE
1
;
Jie ZHANG
1
Author Information
1. 浙江省人民医院（杭州医学院附属人民医院）康复医学科，杭州 310014
- Publication Type:Journal Article
- Keywords:
Akinetic mutism;
Neuroanatomy;
Neuroimaging;
Electrophysiology
- From:
Chinese Journal of Neuromedicine
2025;24(4):415-422
- CountryChina
- Language:Chinese
-
Abstract:
Akinetic mutism (AM) is a neurological disorder characterized by a profound lack of motivation, leading to severe motor and speech impairment or complete loss of function. Due to its clinical resemblance to disorders of consciousness and locked-in syndrome, AM is often misdiagnosed or overlooked, necessitating increased awareness among clinicians. This review summarizes the recent advances in neuroanatomical basis of AM, roles of neuroimaging in AM diagnosis and prognosis, and current therapeutic strategies of AM so as to enhance the awareness of clinicians in AM.
